1764
Government
French fur traders found St. Louis
1803
Politics
Louisiana Purchase makes St. Louis American
1804
Culture
Lewis and Clark depart from near St. Louis
1849
Disaster
Great Fire and cholera epidemic
1874
Engineering
Eads Bridge opens across Mississippi
1904
Culture
World's Fair and Olympics hosted
1917
Civil Rights
East St. Louis Race Massacre
1927
Science
Lindbergh's Spirit of St. Louis flight
1944
Civil Rights
Shelley v. Kraemer reaches Supreme Court
1950
Government
Population peaks at 857,000
1965
Architecture
Gateway Arch completed
2011
Sports
Cardinals win 11th World Series
2014
Civil Rights
Ferguson shooting sparks protests